There are two scenarios where you might see non-convulsive status epilepticus (NCSE):

-Presentation of coma

-Failure to rouse after seemingly successful treatment of a seizure (one article said up to 20% of status epilepticus generates NCSE after resolution of the convulsion)


The gold standard is 48 hours of continuous EEG monitoring. Unfortunately at many EDs we rarely can get EEG monitoring at all. Thus we need to be mindful of some subtle clinical signs.


Clinical signs or triggers that might prompt you to consider non-convulsive status epilepticus:

-***history of epilepsy in someone in an unexplained coma***

-volatile vital signs

-dilated pupils

-twitching (disrobe patients. May especially notice this around the eyes, where it is easier to see)



-failure to rouse after seizure could indicate non-convulsive status epilepticus

-unexplained coma in someone with a history of epilepsy should trigger this possibility

-Disrobe the patient and look for subtle signs of twitching

-Consider autonomic signs – vital signs, pupils